The companies will help customers develop new custom simplex or multiplex assays. Credit: Louis Reed on Unsplash.

Qiagen has collaborated with Niba Labs to provide customised digital PCR (dPCR) assay design services to customers in the biopharma industry.

Biopharma customers can use the dPCR offering to develop cell and gene therapies.

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The partnership will enable the customers of the QIAcuity digital PCR instrument to leverage the combined expertise of Qiagen and Niba Labs for developing new custom simplex or multiplex assays to quantify nucleic acids and optimise existing qPCR assays for digital PCR use.

Niba Labs will involve in the assessment of the assay’s performance and validate them within good manufacturing practice.

Niba Labs chief scientific officer David Dobnik said: “We trust that our partnership with Qiagen will provide the biopharma industry with the most advanced analytical solutions to meet the evolving industry requirements and further advance their cell and gene therapy products.”

Qiagen has also introduced the new CGT Viral Vector Lysis Kit, which allows a standardised workflow from cell lysates to quantify viral titers precisely for several serotypes.

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Designed to be used on the QIAcuity instrument, the new kit can determine viral genome titers in single and multiplex reactions and quantify them over a broad dynamic range with accuracy when integrated with the QIAcuity CGT dPCR assays.

These features make the assay suitable for drug development and quality control in manufacturing.

Qiagen Life Sciences PCR business head and vice-president Michael Scheffler said: “With the introduction of our CGT Viral Vector Lysis Kit, we aim to provide a streamlined protocol for AAV lysis that will bring standardisation to bioprocessing workflows and enhance Standard Operating Procedures, quality control and safety.

“In conjunction with our QIAcuity CGT assays, this kit allows for vector genome titration with remarkable accuracy, repeatability and robustness compared to current workflows.”