Biolife Solutions has patented a method for consistent and repeatable thawing of frozen samples in a bag-format vessel. The method involves measuring temperatures, qualifying sensors, and using multiple heater banks for efficient thawing. Different sensor locations ensure accurate temperature monitoring during the process. GlobalData’s report on Biolife Solutions gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Biolife Solutions, Laboratory automation robots was a key innovation area identified from patents. Biolife Solutions's grant share as of April 2024 was 42%. Grant share is based on the ratio of number of grants to total number of patents.

Method of thawing frozen samples in bag-format vessels

Source: United States Patent and Trademark Office (USPTO). Credit: Biolife Solutions Inc

A recently granted patent (Publication Number: US11938486B2) discloses a method for thawing a frozen sample in a bag-format vessel. The method involves measuring temperatures at different locations of the vessel using multiple sensors, comparing these temperatures to thresholds, and selectively heating the sample using two heater banks based on the temperature readings. The process includes terminating heating once the sample reaches a partially thawed state, ensuring that a solid phase remains in the sample. The termination of heating is determined either by a predetermined time, empirically-derived phase change duration, or deviation from a reference temperature profile.

Furthermore, the patent describes a thawing system that includes a device with two surfaces, multiple sensors, and two heater banks, along with a computer system to control the thawing process. The system is designed to efficiently thaw frozen samples in a bag-format vessel by strategically placing sensors and heater banks, ensuring optimal heating and maintaining the desired consistency of the partially thawed sample. The system's configuration allows for precise control over the thawing process, ensuring that the sample is thawed uniformly and efficiently.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.