AngioDynamics has patented a method using irreversible electroporation to treat infections in patients. The process involves inserting an ablation device with electrodes near the infected tissue, delivering electrical pulses to irreversibly electroporate the infectious cells while preserving the natural tissue scaffold. GlobalData’s report on AngioDynamics gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on AngioDynamics, Target mapping ablation catheters was a key innovation area identified from patents. AngioDynamics's grant share as of May 2024 was 38%. Grant share is based on the ratio of number of grants to total number of patents.

Method for treating infection using irreversible electroporation

Source: United States Patent and Trademark Office (USPTO). Credit: AngioDynamics Inc

A recently granted patent (Publication Number: US11957405B2) discloses a method for treating infected tissue in patients using electrical pulses generated by a generator and delivered between two electrodes placed near the treatment site. The method aims to irreversibly electroporate the infected tissue while preserving the natural tissue scaffold of the patient. Additionally, the treatment site may include a pre-inserted medical device made of a conductive material that functions as a return electrode. The method is designed to reduce the likelihood of irreversible damage to neural structures, promote an immune response, prevent scar tissue formation, and decrease damage to blood vessels within the treatment site. The infected tissue targeted for treatment can include bone or gangrene, caused by various infectious cells such as gram-positive bacteria, Staphylococcus epidermidis, Escherichia coli, and others.

Another aspect of the patent involves a method for decellularizing infected tissue by using electrical pulses delivered through a probe with at least one electrode placed near the treatment site. The pulses aim to irreversibly electroporate cells of the infected tissue while preserving the underlying extracellular matrix. Similar to the previous method, a pre-inserted medical device made of a conductive material serves as a return electrode. This method also focuses on promoting an immune response, maintaining vascular structures, preventing damage to neural structures, and facilitating tissue re-cellularization. The patent further describes a method for treating patients with infected tissue sites using a probe with at least two electrodes, aiming to electroporate the infected tissue, preserve the natural tissue scaffold, and promote an immune response. The treatment site may include various pre-inserted medical devices such as ports, catheters, stents, implants, or prosthetics.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.