DexCom has been granted a patent for a device that measures analyte concentration. The device includes a sensor and a sensing membrane with an enzyme domain, base polymer, and hydrophilic polymer. The enzyme stabilizing reagent in the membrane enhances accuracy. GlobalData’s report on DexCom gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on DexCom, Medical data analysis was a key innovation area identified from patents. DexCom's grant share as of May 2024 was 32%. Grant share is based on the ratio of number of grants to total number of patents.
Patent granted for device measuring analyte concentration with specific membrane
A recently granted patent (Publication Number: US11998329B2) discloses a novel device designed for the measurement of analyte concentration. The device includes a sensor that generates a signal reflecting the analyte concentration, along with a sensing membrane positioned over the sensor. This sensing membrane comprises an enzyme domain containing specific components such as an enzyme stabilizing reagent, a base polymer, and a hydrophilic polymer. The enzyme stabilizing reagent, crucial for enzyme stability, is chosen from a defined group of compounds like cocamidopropyl betaine and phosphatidylcholine. Additionally, the device features a diffusion resistance domain located further from the sensor than the enzyme domain, ensuring precise analyte measurement.
Furthermore, the patent claims detail various configurations and compositions of the device, including the percentage composition of the hydrophilic polymer in the enzyme domain, the selection of specific polymers for the base polymer, and the cross-linking of the enzyme domain for enhanced stability. The device is specifically tailored for continuous measurement of analyte concentration, with a focus on in vivo glucose measurement. The analyte of interest in this context is primarily glucose, and the enzyme stabilizing reagent plays a critical role in ensuring accurate and reliable measurements. The patent also highlights the versatility of the device by listing various enzymes that can be utilized, such as glucose oxidase and cholesterol oxidase, showcasing its potential applications beyond glucose monitoring.
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