Humacyte has been granted a patent for a system that cultivates hollow, tubular tissues using bioreactors with mandrel tubes. The system includes a fluid management system with pumps, valves, and clamps to control fluid flow. This innovation could revolutionize tissue engineering and regenerative medicine. GlobalData’s report on Humacyte gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Humacyte, Prosthetic cardiac valves was a key innovation area identified from patents. Humacyte's grant share as of May 2024 was 50%. Grant share is based on the ratio of number of grants to total number of patents.
System for cultivating hollow, tubular tissues with fluid management
A recently granted patent (Publication Number: US11959060B1) discloses a system for cultivating hollow, tubular tissues using a plurality of bioreactors arranged within drawers. Each bioreactor consists of a luminal space with a tubular tissue on a hollow mandrel tube and an extra-luminal space. The system includes a fluid management system with fluid reservoirs and communication tubes to deliver fluid to the luminal and extra-luminal spaces, allowing for the cultivation of tissues with nutrients and gases dissolved in biomedia fluid.
Furthermore, the system incorporates an environmental control system to maintain optimal conditions for tissue cultivation, along with controllers for system operation and fluid flow management. The patent also details the inclusion of gas dissolving means, height adjustment mechanisms, and flow restrictors within the fluid management system to enhance the cultivation process. Additionally, the system features pumps, valves, and dampeners to facilitate fluid circulation, filling, processing, and draining operations in the bioreactors, ensuring efficient tissue growth and maintenance.
To know more about GlobalData’s detailed insights on Humacyte, buy the report here.
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