Smith & Nephew has been granted a patent for a solid substrate designed to enhance cell or tissue growth, featuring aragonite with specific fluid uptake and contact angle properties. The substrate, shaped with tapered sides, is intended for treating cartilage and bone defects through implantation. GlobalData’s report on Smith & Nephew gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Smith & Nephew, Glucose monitoring wearbles was a key innovation area identified from patents. Smith & Nephew's grant share as of July 2024 was 51%. Grant share is based on the ratio of number of grants to total number of patents.
Optimized solid substrates for cell or tissue growth
The granted patent US12070529B2 outlines a method for treating various defects, disorders, or diseases related to cartilage and bone in subjects. The method involves implanting a solid substrate made from coral or coral derivatives, which is designed to promote cell or tissue growth and restore function. Key characteristics of the solid substrate include a fluid uptake capacity of at least 75% or a contact angle of less than 60 degrees when in contact with a fluid. The substrate is also defined by its geometric features, including a conical or pyramidal frustum shape, tapered sides at an angle of approximately 0.75 to 4 degrees, and at least one flat cross-section at its terminus. The patent specifies various conditions that can be treated, such as osteoarthritis, cartilage defects, and bone disorders, with particular emphasis on joint defects in areas like the knee, ankle, and hip.
Additionally, the patent details the potential use of the solid substrate as an allograft or autograft, with specified height ranges of 5-40 mm or 1-5 cm. The method can be adapted for specific conditions, including osteochondral defects, fractures, and various forms of arthritis. The coral or coral derivatives used in the substrate may be sourced from specific species, including Porites, Goniopora, Millepora, or Acropora. The implantation process may also involve positioning the substrate at an angle relative to the tissue surface being treated. This innovative approach aims to enhance the repair and regeneration of damaged cartilage and bone tissues, providing a potential therapeutic option for patients with musculoskeletal disorders.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
