OraSure Technologies. has been granted a patent for a method that preserves cells and extracellular components in bodily fluids like saliva for medical diagnosis. The technique involves a preservation solution to stabilize samples for analyzing cancer and other conditions, enhancing diagnostic capabilities. GlobalData’s report on OraSure Technologies gives a 360-degree view of the company including its patenting strategy. Buy the report here.
Smarter leaders trust GlobalData
According to GlobalData’s company profile on OraSure Technologies, Biological sampling devices was a key innovation area identified from patents. OraSure Technologies's grant share as of July 2024 was 51%. Grant share is based on the ratio of number of grants to total number of patents.
Cell preservation and analysis for medical diagnosis
The granted patent US12038434B2 outlines a method for diagnosing and monitoring cancer using saliva samples from subjects. The process begins with the collection of a saliva sample, which is then stabilized by mixing it with a preservation solution. This solution contains paraformaldehyde, serum proteins (such as fetal bovine serum), and sodium azide, and is buffered to a pH between 6.4 and 8.4. After storing the mixture at room temperature, the method involves separating extracellular components—proteins, free-floating DNA, and free-floating RNA—from the cells. The final step includes analyzing these components through various molecular techniques, including sequencing, to diagnose or monitor cancer, specifically targeting types such as lung cancer and leukemia.
Additionally, the patent describes methods that not only diagnose and monitor cancer but also determine and administer drug treatments based on the analysis of the saliva sample. The preservation solution's specific composition and the method of separation, which may involve centrifugation, are critical to ensuring the integrity of the analytes. The analysis can include whole genome sequencing, RNA sequencing, DNA sequencing, and epigenetic sequencing, allowing for a comprehensive understanding of the cancer's molecular profile. This innovative approach highlights the potential of non-invasive saliva testing in cancer diagnostics and treatment planning.
To know more about GlobalData’s detailed insights on OraSure Technologies, buy the report here.
Data Insights
From
The gold standard of business intelligence.
Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.
GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
