AlloSource has been granted a patent for an automated tissue processing system designed for demineralization and decellularization. The system features a mixing assembly with a control interface, allowing precise reagent management and automated processing of tissue samples within a specialized mixing chamber. GlobalData’s report on AlloSource gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on AlloSource, Customized implants was a key innovation area identified from patents. AlloSource's grant share as of July 2024 was 44%. Grant share is based on the ratio of number of grants to total number of patents.
Automated tissue processing system for demineralization and decellularization
The patent US12059508B2 describes an automated tissue processing system designed for demineralization or decellularization of tissue portions. Central to this system is a mixing assembly that includes a cannister with a mixing chamber, a reagent inlet for introducing reagents, and a reagent outlet for draining them post-mixing. The assembly features an agitator, a barrier to prevent tissue contact with the agitator, and a motor that allows the agitator to rotate in both directions. Additionally, the system incorporates at least one pump for injecting measured quantities of multiple reagents, a pH meter for monitoring the pH levels of the reagents, and a control and reporting system that facilitates user interaction through a graphical user interface. This interface enables the automated operation of the mixing assembly, ensuring a discrete iteration of the mixing cycle for each reagent.
The claims further specify that the tissue portion can be either bone or soft tissue, and the system may include additional pumps for more reagents. The design of the barrier, which can be a mesh material, mesh bag, or net, is intended to secure the tissue while allowing effective mixing. The barrier is also configured to anchor to the cannister, ensuring stability during the processing. The system's versatility is enhanced by the option to use a multichannel pump or multiple discrete pumps, allowing for precise control over the reagent injection process. Overall, this automated tissue processing system aims to streamline and enhance the efficiency of tissue preparation for various applications.
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