BICO Group has been granted a patent for a particle isolation apparatus designed to isolate particles from suspension samples. The apparatus features a droplet dispenser, mechanical pump, and syphon pump, enabling controlled collection and dispensing of diluted samples onto a target substrate, with a focus on single particle droplets. GlobalData’s report on BICO Group gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on BICO Group, was a key innovation area identified from patents. BICO Group's grant share as of June 2024 was 37%. Grant share is based on the ratio of number of grants to total number of patents.
Particle isolation apparatus for suspensions using droplet dispensing
The granted patent US12000852B2 describes a particle isolation apparatus designed to efficiently isolate particles from a suspension sample. The apparatus features a droplet dispenser device equipped with at least one droplet dispenser, which operates through a combination of negative and positive pressure to collect and dispense droplets. A mechanical pump, potentially a syringe pump, is coupled to the droplet dispenser to facilitate this process, while a syphon pump device, connected to a liquid reservoir positioned lower than the carrier substrate, aids in the aspiration of the suspension sample. The system is controlled by a dispenser control device that manages the operation of both the droplet dispenser and the pumps, ensuring that the suspension sample is diluted in a controlled manner before droplets are dispensed onto a target substrate, with the goal of achieving an average of less than one particle per droplet.
Additionally, the patent outlines a method for isolating particles from a suspension sample, which includes loading a dilution liquid and the suspension sample into the droplet dispenser device, followed by a two-phase aspiration process. The method emphasizes the importance of using a physiological buffer solution as the dilution liquid and allows for the re-capture of droplets containing multiple particles through a recovery vessel. The apparatus and method are designed to ensure residue-free collection of the suspension sample from the carrier substrate, enhancing the efficiency and effectiveness of particle isolation for various applications, including biological research and analysis.
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