Boston Scientific. has filed a patent for a method to crystallize drugs by combining a nucleation initiator, surfactant solution, and amorphous drug form to form a drug precursor dispersion. The method involves incubating the mixture to convert the drug to a crystalline form. GlobalData’s report on Boston Scientific gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Boston Scientific, Prosthetic cardiac valves was a key innovation area identified from patents. Boston Scientific's grant share as of January 2024 was 56%. Grant share is based on the ratio of number of grants to total number of patents.

Method for crystallizing drugs using surfactant and nucleation initiator

Source: United States Patent and Trademark Office (USPTO). Credit: Boston Scientific Corp

The patent application (Publication Number: US20240034741A1) describes a method for crystallizing a drug using a specific process. The method involves forming a solvent solution, a surfactant solution, and a nucleation initiator solution, which are then mixed with amorphous drug particles to create a drug mixture. The surfactant solution is added to the drug mixture to facilitate the crystallization process. Various combinations of solvents, surfactants, and drug types are specified in the claims to achieve the desired crystalline form of the drug.

Furthermore, the method includes additional steps such as incubating the drug precursor dispersion, sonicating the dispersion, filtering the drug microcrystals, and drying them to obtain the final crystalline drug product. The patent also outlines variations in the ratios of solvents and surfactants, as well as specific drug types like everolimus, to be used in the process. Overall, the patent application provides a detailed and specific method for efficiently crystallizing drugs, which could have implications for pharmaceutical manufacturing processes in the future.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies