Danaher has been granted a patent for processes to prepare ion selective membranes that exhibit selectivity for magnesium and calcium ions. The process involves the addition of an ionophore and lipophilic salts containing the respective ions, with applications in electrodes and potentiometric sensors for ion concentration measurement. GlobalData’s report on Danaher gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Danaher, Laboratory automation robots was a key innovation area identified from patents. Danaher's grant share as of June 2024 was 58%. Grant share is based on the ratio of number of grants to total number of patents.

The granted patent US12044652B2 outlines a novel process for preparing ion selective membranes that exhibit selectivity for a primary analyte and an additional ion. The process involves the sequential addition of an ionophore, a lipophilic salt containing the primary analyte, and a lipophilic salt containing the other ion. The claims specify that the molar ratio of the lipophilic salts is critical for achieving a shorter equilibration time when the membrane is exposed to a rinse solution containing both ions. The primary analyte can include magnesium, calcium, zinc, or phosphate ions, with specific examples detailing the use of magnesium and calcium salts. The patent also describes the composition of the ionophore, which may include phenanthroline compounds, and emphasizes the importance of the lipophilic salts having an acidic group.

Additionally, the patent covers the design of the ion selective membrane, which should not have been in contact with an aqueous solution prior to use. It details methods for producing the membrane and its application in measuring ion concentrations, particularly magnesium ions, in liquid samples. The claims extend to the development of electrodes and potentiometric sensors that utilize the described membranes for determining ion concentrations. Furthermore, the patent outlines a diagnostic method for assessing magnesium ion levels in biological samples, which can aid in diagnosing conditions such as hypomagnesemia or hypermagnesemia. Overall, the patent presents a comprehensive approach to enhancing the performance and selectivity of ion selective membranes for analytical applications.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.