Exact Sciences has been granted a patent for a sample collection device designed for stool analysis. The device features a metered sample chamber with a penetrable seal and a flexible sampling rod, enabling efficient sample collection and preparation for analysis. GlobalData’s report on Exact Sciences gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Exact Sciences, Personalized medicine biomarkers was a key innovation area identified from patents. Exact Sciences's grant share as of June 2024 was 44%. Grant share is based on the ratio of number of grants to total number of patents.

Sample collection device for stool analysis

Source: United States Patent and Trademark Office (USPTO). Credit: Exact Sciences Corp

The granted patent US12004726B2 describes a novel collection device designed for the metered sampling of stool. The device features a body with a sample collection chamber that is sealed at the distal end by a penetrable seal and at the proximal end by a septum with an aperture. A flexible sampling rod, which fits through the septum and seals the aperture, is equipped with an asymmetrical beveled tip to minimize collisions with pipette tips or needles during sampling. The rod also includes metering ridges to retain a precise amount of stool, specifically 20 milligrams, within a chamber that can hold between 1 to 5 milliliters of sample. Additionally, the device can contain a solution for preserving the stool sample, with specific formulations including Tris buffer and other stabilizing agents.

Further claims of the patent detail various features of the device, such as the materials used for the body and seals, which may include polypropylene and foil layers, and the ability of the penetrable seal to withstand internal pressure. The device is designed for secure closure with a cap that engages the body, and it can be packaged for mailing, ensuring safe transport of the stool sample. The patent also outlines a system that includes the collection device and an implement for liquid withdrawal, enhancing the usability and functionality of the stool sampling process. Overall, this invention aims to improve the efficiency and reliability of stool sample collection and preservation for diagnostic purposes.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.