Integra LifeSciences has been granted a patent for a method to treat skin wounds using a biodegradable porous polymeric matrix combined with an autograft. This single-stage procedure aims to enhance drainage, promote vessel growth, and reduce scar tissue formation through a specifically designed dermal regeneration matrix. GlobalData’s report on Integra LifeSciences gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Integra LifeSciences, was a key innovation area identified from patents. Integra LifeSciences's grant share as of July 2024 was 53%. Grant share is based on the ratio of number of grants to total number of patents.

Method for skin wound regeneration using a dermal matrix

Source: United States Patent and Trademark Office (USPTO). Credit: Integra LifeSciences Holdings Corp

The patent US12059509B1 outlines a method for treating skin wounds in mammals using a biodegradable porous polymeric matrix. This method involves several steps: first, a sheet of the matrix, characterized by a series of channels that create void areas, is prepared. The channels can have various cross-sectional shapes, including circular, elliptical, and polygonal, and the void space percentage within the matrix is specified to be between 1% and 10%. Following the preparation of the wound bed, the matrix is placed onto the wound, and a skin graft is harvested from a healthy area of the subject and positioned atop the matrix before closing the wound.

The claims further detail the specifications of the biodegradable matrix, including its composition, which may consist of natural or synthetic fibers, and specifically mention a collagen-glycosaminoglycan matrix. The arrangement and size of the channels are also defined, with preferred void space percentages ranging from 1.5% to 5% or 2% to 3%. The matrix's thickness is noted to be between 0.3 mm and 4.0 mm, with specific ranges of 0.5 mm to 2.0 mm. The method is applicable to various types of skin wounds, including full-thickness and partial-thickness wounds, as well as chronic and surgical wounds, indicating its potential versatility in wound care management.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.