Merit Medical Systems. has been granted a patent for methods and devices designed to treat occlusive peripheral vascular diseases. The invention includes a specialized catheter and guidewire system for performing vascular procedures, such as subintimal angioplasty, to effectively address arterial occlusions. GlobalData’s report on Merit Medical Systems gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Merit Medical Systems, Prosthetic cardiac valves was a key innovation area identified from patents. Merit Medical Systems's grant share as of July 2024 was 54%. Grant share is based on the ratio of number of grants to total number of patents.

Devices and methods for treating vascular occlusions

Source: United States Patent and Trademark Office (USPTO). Credit: Merit Medical Systems Inc

The granted patent US12053602B2 outlines a method for treating arterial occlusions through a series of precise steps involving specialized medical devices. The procedure begins with the advancement of a guidewire into the artery's lumen and into the subintimal space adjacent to the occlusion. A first catheter is then introduced over the guidewire into this subintimal space. A stylet guide is advanced from the first catheter towards the lumen beyond the occlusion, maintaining a substantially orthogonal position to the artery's inner layer. The method includes operating a first actuator to move a stylet along a curved path through the stylet guide, allowing the stylet to penetrate the artery wall and access the lumen beyond the occlusion. The design of the stylet guide features a preformed curve to facilitate this process, ensuring that the distal end of the stylet remains within the subintimal space during displacement.

Further claims detail additional steps and components of the method, including the use of a second catheter for blood aspiration to confirm proper placement, and the advancement of a balloon catheter with a stent to create a bypass blood flow lumen adjacent to the occlusion. The patent also describes the mechanisms for operating the actuators, which may include spring-loaded systems, and emphasizes the importance of the stylet's sharp distal end for effective penetration. The method allows for accessing the artery at multiple sites, enhancing the flexibility and effectiveness of treating occlusions. Overall, the patent presents a comprehensive approach to subintimal angioplasty, focusing on precision and the use of specialized tools to navigate and treat arterial blockages.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.