Pulse Biosciences. has been granted a patent for a system that delivers high-voltage electric pulses using large area surface electrodes. The apparatus features a substrate with two electrode patterns designed to create a uniform electrical field, enhancing treatment efficacy in targeted regions. GlobalData’s report on Pulse Biosciences gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Pulse Biosciences, Target mapping ablation catheters was a key innovation area identified from patents. Pulse Biosciences's grant share as of July 2024 was 37%. Grant share is based on the ratio of number of grants to total number of patents.
Electrical energy delivery system using large area surface electrodes
The granted patent US12042653B2 describes a surface applicator apparatus designed for delivering high-voltage electrical pulses to a treatment area. The apparatus features an insulating substrate with two electrodes, each forming a pattern of elongate traces that are significantly longer than they are wide. These patterns are arranged adjacent to one another, maintaining a uniform gap along their lengths, which allows for the creation of a consistent electrical field when connected to a pulse generator. The apparatus includes conductors for electrical communication with the pulse generator, which is capable of delivering sub-microsecond pulses. Additional features may include vacuum ports for securing the electrodes to a patient’s treatment area and the use of insulating materials to enhance performance.
The patent also outlines various configurations and enhancements for the apparatus, such as the use of conductive hydrogels on the electrodes, flexible designs, and specific dimensions for the traces and gaps to optimize the electric field's effectiveness. The method associated with the apparatus involves affixing the electrode applicator to a treatment region on a patient and applying the electrical pulses to generate a uniform electric field. The affixing process can involve adhesive methods, suction, or conforming the applicator to the treatment area. The patent emphasizes the importance of the uniform gap and the dimensions of the electrodes in achieving the desired electric field density, which is critical for effective treatment outcomes.
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