Sartorius has patented a bioreactor for culturing microorganisms or cells with a foam mitigation system using ultrasonic waves. The casing design allows for effective foam control without direct mechanical agitation, enhancing the efficiency of cell culture processes. GlobalData’s report on Sartorius gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Sartorius, Hydrogen fuel cells was a key innovation area identified from patents. Sartorius's grant share as of May 2024 was 50%. Grant share is based on the ratio of number of grants to total number of patents.

Bioreactor with ultrasonic foam mitigation for culturing microorganisms or cells

Source: United States Patent and Trademark Office (USPTO). Credit: Sartorius AG

A newly granted patent (Publication Number: US11999937B2) describes a bioreactor designed for culturing microorganisms or cells while effectively mitigating foam accumulation through the use of ultrasound, eliminating the need for direct mechanical agitation. The bioreactor includes a casing with an interior space for holding culture medium, along with coupling elements for attaching external foam mitigation devices that emit ultrasonic waves to prevent foam build-up. These coupling elements are designed to be transmissive to ultrasound waves, allowing the waves to act on the foam within the bioreactor without direct contact.

Additionally, the patent outlines a system for culturing microorganisms or cells that incorporates the innovative bioreactor design. This system includes inlet and outlet ports for introducing and removing fluids, respectively, along with a foam mitigation device equipped with an ultrasonic wave generator. The generator transmits ultrasonic waves through the casing to target foam build-up within the bioreactor. The system also features a stirring device for mixing the culture medium without the need for mechanical agitation of the foam, enhancing the efficiency of the culturing process. Overall, the patented technology offers a novel approach to bioreactor design, improving the cultivation of microorganisms and cells while addressing the common issue of foam accumulation in a non-intrusive manner.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.