Sysmex has patented a fluorescence image display method and analyzer that enhances cell classification accuracy by minimizing operator skill influence. The system captures fluorescence images, analyzes them using software, and displays results alongside auxiliary information to aid visual analysis of fluorescent markers in individual cells. GlobalData’s report on Sysmex gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Sysmex, Laboratory automation robots was a key innovation area identified from patents. Sysmex's grant share as of June 2024 was 50%. Grant share is based on the ratio of number of grants to total number of patents.
Fluorescence image analysis method for cell classification
The granted patent US12026880B2 outlines a fluorescence image display method designed to enhance the analysis and visualization of fluorescence images obtained from individual cells. The method involves capturing a fluorescence image of a cell with target sites labeled by two different fluorescent dyes, each emitting distinct colors. The process includes software-based image analysis that identifies and classifies fluorescence bright spots corresponding to these dyes. The results of this analysis, along with auxiliary information that aids in visual measurements—such as the distance between the bright spots—are displayed alongside the original fluorescence image. This auxiliary information may also include visual aids like ruled lines, figures representing bright spots, and quality metrics of the fluorescence image.
Additionally, the patent describes various functionalities of the fluorescence image display method, including the ability to classify cells based on their fluorescence characteristics and to identify images that do not meet classification criteria. The method allows for interactive adjustments to the analysis results through an operation unit, enabling users to refine their visual assessments. The auxiliary information can be tailored based on user identification and preferences, enhancing the overall usability of the system. The fluorescence image analyzer described in the patent comprises essential components such as a light source, imaging unit, processing unit, and display unit, all working in concert to facilitate detailed analysis and visualization of cellular fluorescence data.
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