Waters has patented a sample preparation device for affinity capture and purification, combining dispersive and flow-through designs. The method involves adding a sample, washing, and eluting to isolate and purify target analytes. The device includes sorbent particles with immobilized affinity ligands like polymer imprinted materials and oligosaccharides. GlobalData’s report on Waters gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Waters, was a key innovation area identified from patents. Waters's grant share as of May 2024 was 44%. Grant share is based on the ratio of number of grants to total number of patents.
Affinity isolation and purification method using sample preparation device
A recently granted patent (Publication Number: US11998862B2) discloses a method for performing an affinity isolation and purification procedure. The method involves adding a sample fluid containing a target analyte to a device with an internal structure comprising a reservoir, a well, a fluid passageway, sorbent particles, and a filter element. The sorbent particles contain immobilized affinity ligands, including polymer imprinted materials and oligosaccharides. The process includes dispersing the sorbent particles in the sample fluid, removing unbound substances, washing the sorbent particles, adding an elution fluid to release the target analyte, and finally removing the purified target analyte from the device.
Furthermore, the method allows for various techniques to disperse the sorbent particles in the sample fluid, such as shaking the device on a shaker device, using a vortex mixer, or aspirating and dispensing the sample fluid and particles. The patent also mentions different methods for removing the sample fluid, washing fluid, and elution fluid from the device, including centrifugation, applying vacuum or positive pressure to the device. Additionally, the method may involve adding a conditioning buffer to the reservoir before adding the sample fluid and capping the openings for receiving fluids or the fluid passageway to control the flow of fluids during the procedure.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
