The tool integrates AI classifiers with Whole Slide Images. Credit: Deciphex.

Charles River Laboratories has partnered with digital pathology company Deciphex to introduce Patholytix Foresight, a non-clinical AI decision support tool designed to enhance toxicologic pathology assessments. 

This tool is intended to help accelerate primary evaluation and peer review processes, thereby facilitating faster decision-making in drug discovery and safety assessment. 

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Patholytix Foresight provides toxicologic pathologists with advanced visual tools that promote efficiency, consistency, and accuracy in their assessments. 

Charles River chief scientific officer and corporate senior vice-president Julie Frearson said: “AI-powered solutions are accelerating the pace and efficiency of drug development, and the launch of Patholytix Foresight marks a significant milestone in our collaborative efforts to enhance the digital transformation of toxicological pathology.” 

The tool leverages an extensive data warehouse to incorporate organ-based lesion classifiers. It is built on Deciphex’s non-clinical workflow platform, Patholytix 4.0.  

Patholytix Foresight also integrates AI classifiers with Whole Slide Images (WSI) to streamline workflows and assist pathologists in identifying critical features in tissue samples. 

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Deciphex chief scientific officer Pierre Moulin said: “In collaboration with Charles River Laboratories, we look forward to bringing Patholytix Foresight to the forefront of digital pathology, empowering pathologists worldwide with cutting-edge AI technology for more efficient and accurate toxicological assessments.  

“This advance is part of our collective vision to enable AI-empowered and regulated digital primary review of safety studies.” 

In February 2024, Diagnexia signed a collaborative agreement with Kenya’s Aga Khan University Hospital to enhance pathology services and spearhead advancements in AI-driven diagnostics.