Analysis by GlobalData estimates that the LVAD device market will reach $2.24bn by 2033, as heart failure prevalence continues to rise. Image credit: Shutterstock/Jo Panuwat D.

Magenta Medical has advanced a step closer to regulatory approval for its Elevate heart pump system, after the company announced it had completed enrolment in an early feasibility study for the device.

Elevate – dubbed by Magenta as the ‘world’s smallest heart pump’ – was used in 15 patients to provide temporary mechanical circulatory support during high-risk percutaneous coronary intervention (HR-PCI) procedures. Magenta’s percutaneous Left Ventricular Assist Device (pLVAD) is inserted over a guidewire through sheaths via the groin. According to the Israel-based company, it has developed technology that “miniaturises a powerful blood pump to fit an 8 Fr delivery system – the smallest crimping profile of any such device”.

Go deeper with GlobalData

Data Insights

The gold standard of business intelligence.

Find out more

Related Company Profiles

View all

The size of Magenta’s device means it can be applied less invasively, compared to the larger traditional LVADs which usually require open heart surgery.

The US Food and Drug Administration (FDA) approved the use of the Elevate in an Early Feasibility Study, which commenced in mid-June 2023.

The trial (NCT05727059) is a prospective, single-arm, multi-centre, interventional study. Primary outcome measures are the rate of major device-related adverse events and how successful the device is in providing haemodynamic support. Both these outcomes are assessed from device insertion to removal, a period of up to six hours.

Analysis by GlobalData estimates that the LVAD device market will reach $2.24bn by 2033, as heart failure prevalence continues to rise.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Dr. Samin Sharma, Director of Interventional Cardiology at the Mount Sinai Health System in New York City, who performed the first US procedure, said: “Having now used the system in nine complex, high-risk PCI cases, I can truly appreciate its advantages.”

“As I see it, the three cardinal features of the Elevate pLVAD – small insertion profile, ease-of-use, and high pump flow – will enable us to benefit many more appropriately selected complex PCI patients, where current devices are limited. Elevate is advanced over the wire, fully crimped and covered. This makes it possible to navigate the device smoothly even through hostile vascular environments, which is very important, as atherosclerosis affects the entire arterial tree.”

In May 2023, the company raised $55m to help fund clinical programmes for the device.