Daily Newsletter

05 June 2024

Daily Newsletter

05 June 2024

Bruker launches mass spectrometry-based tissue imaging device

Bruker unveiled the device at the annual American Society of Mass Spectrometry (ASMS) conference, in Anaheim, California.

Ross Law June 05 2024

Bruker has launched its neofleX Imaging Profiler MALDI-TOF/TOF for mass spectrometry imaging (MSI) applications.

Suitable for mass spectrometry-based tissue imaging, Bruker states that the device addresses the unmet needs of moving from discovery imaging to translational and clinical tissue research.

NeofleX is also compatible with the MALDI-ISH method announced at ASMS 2024 by AmberGen.

MALDI-ISH multiplexes imaging of up to 12 oligomers of interest (RNA/DNA) for multi-omic spatial tissue research in neuroscience, infectious disease, and oncology.

In addition, the company says the neofleX excels at providing more insight per pixel through multi-omic spatial biology data from tissue sections that can positively correlate targeted proteins with glycans, metabolites, lipids, endogenous peptides, xenobiotics, and now RNA/DNA.

The neofleX is compatible with existing Bruker software and hardware, including its MALDI Imaging software and consumables ecosystems such as IntelliSlides and SCiLSautopilot – tools intended to simplify sample tracking, preparation, and analysis and to automate mass-spec imaging runs.

According to Dr Michael Easterling, vice president of MSI for Bruker’s life sciences mass spectrometry division, the device’s multimodal software and workflows on the benchtop will support a range of biopharma and clinical research tasks.

Easterling said: “NeofleX brings novel capabilities to spatial biology, including spatial proteomics combined with unique multiomics correlations for developing actionable biological insights.”

The device’s launch follows Bruker’s recent acquisition of ELITechGroup for $942m.

Last year, Bruker entered a partnership with Advanced Diagnostics to validate the use of the company’s respective Arc and MALDI Biotyper systems.

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